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A-867744

$80$750

Products Details

Product Description

– A-867744 is a highly potent and selective type II positive allosteric modulator (PAM) of the alpha7 nicotinic acetylcholine receptors (nAChR) with an EC50 of 1.0 μM[1].

Web ID

– HY-12149

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C20H19ClN2O3S

CAS Number

– 1000279-69-5

Molecular Weight

– 402.89

Compound Purity

– 99.76

SMILES

– O=S(C1=CC=C(C=C1)N2C(C)=C(C=C2C3=CC=C(C=C3)Cl)C(CC)=O)(N)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : ≥ 100 mg/mL

Target

– nAChR

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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