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A 839977

SKU T14076-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 59 CAD through 234 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)5 mg

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Products Details

Product Description

– A-839977 is a selective P2X7 receptor antagonist with anti-inflammatory and analgesic properties, inhibiting BzATP-induced calcium efflux from the P2X7 receptor, and is used in the study of renal fibrosis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T14076

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H14Cl2N6O

References

– Honore P, et al. The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1alphabeta knockout mice. Behav Brain Res. 2009 Dec 1;204(1):77-81.

CAS Number

– 870061-27-1

Molecular Weight

– C19H14Cl2N6O

Compound Purity

– 0.9801

SMILES

– Clc1cccc(c1Cl)-n1nnnc1NCc1ccccc1Oc1ccccn1

Target

– Others

Pathway

– Metabolism|||Membrane transporter/Ion channel|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.