Download Files:

5-Azacytidine

SKU T1339-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 53 CAD through 162 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)100 mg 200 mg 50 mg 500 mg

Clear

Products Details

Product Description

– 5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autophagy and has antitumor activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1339

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C8H12N4O5

Citations

– 1. Wang W, Ren S, Lu Y, et al. Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production. The EMBO Journal. 2021 Jun 1;40(11):e106771. doi: 10.15252/embj.2020106771. Epub 2021 Apr 28. 2. Łagosz-Ćwik K, Melnykova M, Nieboga E, et al.Mapping of DNA methylationsensitive cellular processes in gingival and periodontal ligament fibroblasts in the context of periodontal tissue homeostasis.Frontiers in Immunology.2023, 14. 3. Small S H, Perez R E, Beauchamp E M, et al.Targeting SLFN11-Regulated Pathways Restores Chemotherapy Sensitivity in AML.Blood Neoplasia.2024: 100037.

References

– Gailhouste L, et al. Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells. Cell Death Dis. 2018 May 1;9(5):468.

CAS Number

– 320-67-2

Molecular Weight

– C8H12N4O5

Compound Purity

– 0.9962

SMILES

– O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)N=C2

Target

– Others

Pathway

– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Autophagy|||Microbiology/Virology

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.