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Products Details
Product Description
– 4-Chlorophenylguanidine hydrochloride is a potent ASIC3 positive allosteric modulator and reverses the effects of ASIC3 desensitization. 4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity. 4-Chlorophenylguanidine hydrochloride offers a chemical backbone for the design of new ASIC3 ligands to study ASIC3 in vivo[1].
Web ID
– HY-100939
Shipping
– Room temperature
Molecular Formula
– C7H9Cl2N3
References
– [1]Amruta S Agharkar, et al. 4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator. J Pharmacol Sci. 2017 Mar;133(3):184-186.
CAS Number
– 14279-91-5
Molecular Weight
– 206.07
SMILES
– NC(NC1=CC=C(Cl)C=C1)=N.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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