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Products Details
Product Description
– 2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-140125
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H16O4S3
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number
– 1807530-16-0
Molecular Weight
– 308.44
SMILES
– O=S(OCCSSCCO)(C1=CC=C(C)C=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker;Disulfide Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
