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Product Description
– 2-Deoxy-D-galactose is a glucose analog. 2-Deoxy-D-galactose inhibits glycolysis to inhibits tumor growth. 2-Deoxy-D-galactose is a substance interfering with the fucosylation of glycomacromolecules and impairing memory consolidation in various learning tasks. 2-Deoxy-d-galactose hinders glycoprotein fucosylation in vivo[1].
Web ID
– HY-131892
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C6H12O5
References
– [1]Keppler DO, et al. The trapping of uridine phosphates by D-galactosamine. D-glucosamine, and 2-deoxy-D-galactose. A study on the mechanism of galactosamine hepatitis. Eur J Biochem. 1970 Dec;17(2):246-53.|[2]Krug M, et al. The amnesic substance 2-deoxy-D-galactose suppresses the maintenance of hippocampal LTP. Brain Res. 1991 Feb 1;540(1-2):237-42. |[3]Lorenzini CG, et al. 2-Deoxy-D-galactose effects on passive avoidance memorization in the rat. Neurobiol Learn Mem. 1997 Nov;68(3):317-24.|[4]Smith DF, Keppler DO. 2-Deoxy-D-galactose metabolism in ascites hepatoma cells results in phosphate trapping and glycolysis inhibition. Eur J Biochem. 1977 Feb 15;73(1):83-92.
CAS Number
– 1949-89-9
Molecular Weight
– 164.16
Compound Purity
– 50.0
SMILES
– O=CC[C@H]([C@H]([C@@H](CO)O)O)O
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease
Solubility
– H2O : 250 mg/mL (ultrasonic)|Methanol : 125 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Reference compound
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