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17-AEP-GA

Products Details

Product Description

– 17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin[1].

Web ID

– HY-133570

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C34H50N4O8

References

– [1]Katarzyna Miekus, et al. 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. Oncol Rep. 2012 Nov;28(5):1903-9.

CAS Number

– 75747-23-8

Molecular Weight

– 642.78

SMILES

– O=C(C(NCCN1CCCC1)=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=CC=C(C)C3=O)C=C(N3)C2=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– ADC Cytotoxin;HSP

Isoform

– HSP90;Traditional Cytotoxic Agents

Pathway

– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– ADC Related

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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