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1-Ethynylpyrene
$51 – $340
Products Details
Product Description
– 1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1]. 1-Ethynylpyrene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-131452
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H10
References
– [1]Naijue Zhu, et al. Ethynyl and Propynylpyrene Inhibitors of Cytochrome P450. J Chem Crystallogr. 2010 Apr 1;40(4):343-352.
CAS Number
– 34993-56-1
Molecular Weight
– 226.27
Compound Purity
– 99.53
SMILES
– C#CC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 9.09 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Cytochrome P450
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
