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1-Deoxynojirimycin
$72 – $369
Products Details
Product Description
– 1-Deoxynojirimycin (Duvoglustat) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin possesses antihyperglycemic, anti-obesity, and antiviral features[1][2].
Web ID
– HY-14860
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C6H13NO4
References
– [1]Chaluntorn Vichasilp,et al. Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction. LWT – Food Science and Technology. Volume 45, Issue 2, March 2012, Pages 226-232|[2]Gao K, et al. 1-Deoxynojirimycin: Occurrence, Extraction, Chemistry, Oral Pharmacokinetics, Biological Activities and In Silico Target Fishing. Molecules. 2016 Nov 23;21(11). pii: E1600.|[3]Liu Q, et al. 1-Deoxynojirimycin Alleviates Insulin Resistance via Activation of Insulin Signaling PI3K/AKT Pathway in Skeletal Muscle of db/db Mice. Molecules. 2015 Dec 4;20(12):21700-14.
CAS Number
– 19130-96-2
Molecular Weight
– 163.17
Compound Purity
– 98.0
SMILES
– O[C@@H]1[C@@H](CO)NC[C@H](O)[C@H]1O
Clinical Information
– Phase 2
Research Area
– Metabolic Disease
Solubility
– H2O : ≥ 34 mg/mL
Target
– Glucosidase;PI3K
Pathway
– Metabolic Enzyme/Protease;PI3K/Akt/mTOR
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
