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EVP-0015962
Price range: 2,432 CAD through 4,000 CAD
Products Details
Product Description
– EVP-0015962, which is bioavailable orally, is a potent and selective gamma-secretase regulator in vitro and in vivo, detectable in the brain.
Web ID
– T31733
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H19ClF6O3
References
– Rogers K, Felsenstein KM, Hrdlicka L, Tu Z, Albayya F, Lee W, Hopp S, Miller MJ, Spaulding D, Yang Z, Hodgdon H, Nolan S, Wen M, Costa D, Blain JF, Freeman E, De Strooper B, Vulsteke V, Scrocchi L, Zetterberg H, Portelius E, Hutter-Paier B, Havas D, Ahlijanian M, Flood D, Leventhal L, Shapiro G, Patzke H, Chesworth R, Koenig G. Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice. Mol Neurodegener. 2012 Dec 18;7:61. doi: 10.1186/1750-1326-7-61. PubMed PMID: 23249765; PubMed Central PMCID: PMC3573960.
CAS Number
– 1447811-26-8
Molecular Weight
– C22H19ClF6O3
SMILES
– O(CC(F)(F)F)C1=C(C=C([C@@H](CC2CCC2)C(O)=O)C=C1Cl)C3=CC=C(C(F)(F)F)C=C3
Target
– Dehydrogenase
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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