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DM1-SMe
Price range: 48 CAD through 917 CAD
Products Details
Product Description
– DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.
Web ID
– T21408
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C36H50ClN3O10S2
References
– Wood AC, et al. Initial testing (Stage 1) of the antibody-maytansinoid conjugate, IMGN901 (Lorvotuzumab mertansine), by the pediatric preclinical testing program. Pediatr Blood Cancer. 2013;60(11):1860-1867.
CAS Number
– 138148-68-2
Molecular Weight
– C36H50ClN3O10S2
Compound Purity
– 0.9719
SMILES
– [H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)c1cc(CC(C)=C/C=C[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)cc(OC)c1Cl)OC(=O)[C@H](C)N(C)C(=O)CCSSC
Pathway
– Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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