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Parthenolide
Price range: 80 CAD through 190 CAD
Products Details
Product Description
– Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB inhibitor and also specifically inhibits HDAC1 protein, but is inactive against other class I/II HDACs. Parthenolide has anti-inflammatory, anti-tumor, and anti-viral activities.
Web ID
– T2140
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H20O3
Citations
– 1. Fu Z, Duan Y, Pei H, et al.Discovery of Potent, Specific, and Orally Available NLRP3 Inflammasome Inhibitors Based on Pyridazine Scaffolds for the Treatment of Septic Shock and Peritonitis.Journal of Medicinal Chemistry.2024
References
– Nakshatri, H., Appaiah, H., Anjanappa, M., Gilley, D., Tanaka, H., & Badve, S. et al. (2015). NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT. Cell Death & Disease, 6(1), e1608-e1608. doi: 10.1038/cddis.2014.569
CAS Number
– 20554-84-1
Molecular Weight
– C15H20O3
Compound Purity
– 0.9933
SMILES
– CC1=C/CC[C@@]2(C)O[C@H]2[C@H]2OC(=O)C(=C)[C@@H]2CC1
Pathway
– DNA Damage/DNA Repair|||NF-κB|||Apoptosis|||Autophagy|||Chromatin/Epigenetic
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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