Ibudilast
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Ibudilast

SKU T2137-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 162 CAD

Products Details

Product Description

– Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.

Web ID

– T2137

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H18N2O

Citations

– 1. Zhou D, Yang S, Yan H, et al. SC75741, a novel c-Abl inhibitor, promotes the clearance of TDP25 aggregates via ATG5-dependent autophagy pathway. Frontiers in Pharmacology. 2021: 2891. 2. Chen Y, Wang H, Ying Z, et al. Ibudilast enhances the clearance of SOD1 and TDP-43 aggregates through TFEB-mediated autophagy and lysosomal biogenesis: The new molecular mechanism of ibudilast and its implication for neuroprotective therapy. Biochemical and Biophysical Research Communications. 2020

References

– Yamazaki T, et al. Eur J Pharmacol. 2010 Oct 29.

CAS Number

– 50847-11-5

Molecular Weight

– C14H18N2O

Compound Purity

– 0.9994

SMILES

– C(C(C)C)(=O)C1=C2N(N=C1C(C)C)C=CC=C2

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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