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SC-514
Price range: 48 CAD through 725 CAD
Products Details
Product Description
– SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
Web ID
– T2118
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C9H8N2OS2
Citations
– 1. Liu Y, Wang J, Chen J, et al. Upregulation of miR-520c-3p via Hepatitis B Virus Drives Hepatocellular Migration and Invasion through the PTEN/AKT/NF-κB Signaling Pathway. Molecular Therapy-Nucleic Acids. 2022
2. Zhu Y, Xiao Y, Kong D, et al. Down-Regulation of miR-378d Increased Rab10 Expression to Help Clearance of Mycobacterium tuberculosis in Macrophages. Frontiers in cellular and infection microbiology. 2020, 10: 108.
References
– Kishore N, et al. J Biol Chem, 2003, 278(35), 32861-32871.
CAS Number
– 354812-17-2
Molecular Weight
– C9H8N2OS2
Compound Purity
– 0.9988
SMILES
– NC(=O)c1sc(cc1N)-c1ccsc1
Target
– GABA Receptor
Pathway
– Proteases/Proteasome|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||NF-κB|||MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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