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Danusertib
Price range: 82 CAD through 1,744 CAD
Products Details
Product Description
– Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Danusertib binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed.
Web ID
– T2094
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H30N6O3
Citations
– 1. Cheng S, Jin P, Li H, et al. Evaluation of CML TKI Induced Cardiovascular Toxicity and Development of Potential Rescue Strategies in a Zebrafish Model. Frontiers in Pharmacology. 2021: 2866.
References
– Carpinelli P, et al. Mol Cancer Ther, 2007, 12 Pt 1, 3158-3168.
CAS Number
– 827318-97-8
Molecular Weight
– C26H30N6O3
Compound Purity
– 0.982
SMILES
– CO[C@@H](C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1)c1ccccc1
Pathway
– Apoptosis|||Cell Cycle/Checkpoint|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Autophagy|||Cytoskeletal Signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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