ETP-46464

SKU T2084-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 741 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2084

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H22N4O2

Citations

– 1. He Q, Zhang Y, Li W, et al.Inhibition of PRMT5 moderately suppresses prostate cancer growth in vivo but enhances its response to immunotherapy.Cancer Letters.2024: 217214.

References

– Toledo LI, et al. Nat Struct Mol Biol, 2011, 18(6), 721-727.

CAS Number

– 1345675-02-6

Molecular Weight

– C30H22N4O2

Compound Purity

– 0.9956

SMILES

– CC(C)(C#N)c1ccc(cc1)N1C(=O)OCc2cnc3ccc(cc3c12)-c1cnc2ccccc2c1

Pathway

– DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.