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LCL161
Price range: 101 CAD through 766 CAD
Products Details
Product Description
– LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP (IC50=35 nM) in HEK293 cells and also inhibits cIAP1 (IC50=0.4 nM) in MDA-MB-231 cells. LCL161 has potential antitumor activity.
Web ID
– T2080
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H33FN4O3S
Citations
– 1. Chen H, Li Y, Wu J, et al. RIPK3 collaborates with GSDMD to drive tissue injury in lethal polymicrobial sepsis. Cell Death & Differentiation. 2020: 1-18
References
– Weisberg E, et al. Leukemia, 2010, 24(12), 2100-2109.
CAS Number
– 1005342-46-0
Molecular Weight
– C26H33FN4O3S
Compound Purity
– 0.9972
SMILES
– CNC(C)C(=O)NC(C1CCCCC1)C(=O)N1CCCC1c1nc(cs1)C(=O)c1ccc(F)cc1
Target
– E3 Ligase Ligand-Linker Conjugate
Pathway
– Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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