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LCL161

SKU T2080-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 101 CAD through 766 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP (IC50=35 nM) in HEK293 cells and also inhibits cIAP1 (IC50=0.4 nM) in MDA-MB-231 cells. LCL161 has potential antitumor activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2080

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H33FN4O3S

Citations

– 1. Chen H, Li Y, Wu J, et al. RIPK3 collaborates with GSDMD to drive tissue injury in lethal polymicrobial sepsis. Cell Death & Differentiation. 2020: 1-18

References

– Weisberg E, et al. Leukemia, 2010, 24(12), 2100-2109.

CAS Number

– 1005342-46-0

Molecular Weight

– C26H33FN4O3S

Compound Purity

– 0.9972

SMILES

– CNC(C)C(=O)NC(C1CCCCC1)C(=O)N1CCCC1c1nc(cs1)C(=O)c1ccc(F)cc1

Target

– E3 Ligase Ligand-Linker Conjugate

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.