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NNK

SKU T20533-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 88 CAD through 1,098 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– NNK is a nicotinic nitrosylated derivative. It activates ERK1/2 and PKCα, and activates Bcl2 phosphorylation at Ser70, as well as c-Myc at Thr58 and Ser62.It can be used to construct mouse models of lung cancer, as well as to induce proliferation and survival of human lung cancer cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T20533

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C10H13N3O2

Citations

– 1. Han G, Sinjab A, Rahal Z, et al.An atlas of epithelial cell states and plasticity in lung adenocarcinoma.Nature.2024, 627(8004): 656-663.

References

– Cheng G, Li J, Zheng M, Zhao Y, Zhou J, Li W. NNK, a tobacco-specific carcinogen, inhibits the expression of lysyl oxidase, a tumor suppressor. Int J Environ Res Public Health. 2014 Dec 23;12(1):64-82.

CAS Number

– 64091-91-4

Molecular Weight

– C10H13N3O2

Compound Purity

– 0.9992

SMILES

– CN(CCCC(=O)c1cccnc1)N=O

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.