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SIRT6-IN-4
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– SIRT6-IN-4 (Compound 10d) is a selective inhibitor of SIRT6 with an IC50 of 5.68 μM. It inhibits the proliferation of MCF-7 cells, with an IC50 of 8.30 μM, and causes cell cycle arrest at the G2/M phase. Additionally, SIRT6-IN-4 impedes cell migration and invasion of MCF-7 and induces apoptosis. In mouse models, this compound exhibits antitumor activity.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T204538
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H18ClN5O
Molecular Weight
– C26H18ClN5O
SMILES
– C1=CC=NC(=C1)CNC(=O)C2=NC=C3C(=C2)C4=C(N3CC5=CC=C(C=C5)C#N)C=CC(=C4)Cl
Target
– Others
Pathway
– DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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