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BCL-XL-IN-3
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– BCL-XL-IN-3 (Compound 11) is an inhibitor of BCL-XL, with a Ki of less than 0.01 nM. It suppresses cell viability in both normal Molt-4 cells and digitonin-permeabilized Molt-4 cells, with EC50 values of 77.8 nM and 0.07 nM, respectively. BCL-XL-IN-3 can be utilized as an ADC toxin for synthesizing Clezutoclax.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T203416
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C46H55N7O6S
CAS Number
– 1949840-87-2
Molecular Weight
– C46H55N7O6S
SMILES
– C(C12CC3(OCCNCC[C@@H](CO)O)CC(C)(C1)CC(C)(C2)C3)N4C(C)=C(C=N4)C5=C(C(O)=O)N=C(C=C5)N6CC7=C(C(NC8=NC=9C(S8)=CC=CC9)=O)C=CC=C7CC6
Target
– Lipoxygenase
Pathway
– Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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