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F-SLOH
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– F-SLOH is a near-infrared fluorescent probe (NIRF). In the brains of 5XFAD and 3XTg-AD mice, F-SLOH significantly reduces the levels of Aβ oligomers, Tau aggregates and plaques, as well as amyloid precursor protein (APP) and its metabolites, via the autophagic-lysosomal degradation pathway (ALP). Additionally, F-SLOH diminishes astrocyte activation and microglial proliferation, effectively alleviating neuroinflammation. It also mitigates hyperphosphorylated Tau protein aggregates, improves synaptic defects, enhances synaptic memory function, and ameliorates cognitive impairment in AD model mice.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T202718
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H30ClFN2O3
CAS Number
– 1620896-55-0
Molecular Weight
– C30H30ClFN2O3
SMILES
– C(COCCOC)N1C=2C(C=3C1=CC=C(F)C3)=CC(/C=C/C=4C5=C([N+](CCO)=CC4)C=CC=C5)=CC2.[Cl-]
Target
– ADC Linker
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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