Tesevatinib tosylate

Name: Tesevatinib tosylate | Buy Online | Immunomart
Brand: TargetMol
SKU: T201865-10 mg

SKU T201865-10 mg Category Small Compound Brand: TargetMol

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Tesevatinib tosylate (XL-647 tosylate) is an orally administered epidermal growth factor receptor (EGFR) inhibitor that can cross the blood-brain barrier. It significantly reduces cell viability with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Additionally, Tesevatinib tosylate inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM), demonstrating antitumor activity by inhibiting tumor proliferation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T201865

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H33Cl2FN4O5S

CAS Number

– 1000599-06-3

Molecular Weight

– C31H33Cl2FN4O5S

SMILES

– S(=O)(=O)(O)C1=CC=C(C)C=C1.N(C=1C2=C(C=C(OC[C@@H]3C[C@]4([C@@](C3)(CN(C)C4)[H])[H])C(OC)=C2)N=CN1)C5=C(F)C(Cl)=C(Cl)C=C5

Pathway

– JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.