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XJTU-L453

SKU T200390-25 mg Category Small Compound Brand: TargetMol

Price range: 1,670 USD through 2,800 USD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

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Products Details

Product Description

– XJTU-L453, a PI3Kα inhibitor, exhibits an IC50 of 0.4 nM. It inhibits the proliferation of breast cancer cell lines T47D and MCF7, with IC50 values of 0.2 μM and 0.5 μM respectively. Additionally, XJTU-L453 disrupts the PI3K pathway, leading to cell cycle arrest and cell apoptosis (apoptosis). It also demonstrates antitumor activity in MCF7 xenograft mice.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T200390

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H22N4O3

CAS Number

– 3008290-92-1

Molecular Weight

– C22H22N4O3

SMILES

– O([C@H](C(N)=O)C)C=1C=C2C(C=3C(CO2)=CC=C(C3)C=4C=C(NCC)N=CN4)=CC1

Target

– Adrenergic Receptor

Pathway

– PI3K/Akt/mTOR signaling|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.