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PAP-1

SKU TQ0179-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 91 CAD through 1,323 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, orally active Kv1.3 blocker with an EC50 of 2 nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TQ0179

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H18O5

Citations

– 1. Chen Y, Zhi Y, Zhong H, et al.Inhibition of Kv1. 3 channel restrains macrophage M2 polarization and ameliorates renal fibrosis via regulating STAT6 phosphorylation.Pharmacological Research.2025: 107623.

References

– Schmitz A, et al. Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases. Mol Pharmacol. 2005 Nov;68(5):1254-70.

CAS Number

– 870653-45-5

Molecular Weight

– C21H18O5

Compound Purity

– 0.9935

SMILES

– O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.