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Products Details
Product Description
– EIPA (L593754) is a TRPP3 channel inhibitor (IC50=10.5 μM) and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy, and can be used in inflammation and tumor studies.
Web ID
– TQ0157
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H18ClN7O
Citations
– 1. Wang C, Hu R, Wang T, et al.A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A.Journal of Biological Chemistry.2023: 104605.
2. Chen L, Xu C, Xu H, et al.RVG29-modified oncolytic herpes simplex virus for intracranial tumor treatment.Nano Today.2025, 61: 102573.
References
– Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85.
CAS Number
– 1154-25-2
Molecular Weight
– C11H18ClN7O
Compound Purity
– 0.9997
SMILES
– CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N
Pathway
– Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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