Products Details

Product Description

– Peptide comprising residues 33 – 57 of the JNK binding (δ) domain of human c-Jun. Disrupts JNK/c-Jun interaction leading to inhibition of serum-induced c-Jun phosphorylation, up-regulation of p21cip/waf and modulation of inflammatory gene expression. Specifically induces apoptosis in HeLa tumor cells.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TP2134

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C121H210N36O34S

References

– Holzberg et al (2003) Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN d domain induces apoptosis and affects a distinct set of interleukin-1 induced inflammatory genes. J.Biol.Chem. 278 40213 PMID: 12832416

CAS Number

– 610273-01-3

Molecular Weight

– C121H210N36O34S

SMILES

– C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CO)=O)CCSC)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)C)=O)CC(O)=O)=O)CCC1)C(C)C)=O)=O)CO)=O)CC(C)C)=O)CCCCN)(=O)N2[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CCCCN)=O)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)=O)CCC2

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.