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Angoline

SKU TN6739-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 96 CAD through 1,246 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50: 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TN6739

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H21NO5

References

– Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91.

CAS Number

– 21080-31-9

Molecular Weight

– C22H21NO5

Compound Purity

– 0.9996

SMILES

– COC1N(C)c2c(ccc3cc4OCOc4cc23)-c2ccc(OC)c(OC)c12

Pathway

– Immunology/Inflammation|||JAK/STAT signaling|||Stem Cells

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.