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Isoangustone A
864 CAD
Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoangustone A dampens mesangial sclerosis associated with inflammation in response to high glucose through hindering TGF-β and NF-κB signaling. Isoangustone A also shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– TN4263
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H26O6
CAS Number
– 129280-34-8
Molecular Weight
– C25H26O6
SMILES
– CC(C)=CCc1cc(cc(O)c1O)-c1coc2cc(O)c(CC=C(C)C)c(O)c2c1=O
Pathway
– Cytoskeletal Signaling|||NF-κB|||MAPK|||Immunology/Inflammation|||Stem Cells|||Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Proteases/Proteasome
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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