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4,5-Dimethoxycanthin-6-one

SKU TN3013-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 117 CAD through 1,203 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– 4,5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity against Staphylococcus aureus and its drug-resistant strains. It is a potent, non-competitive inhibitor of CYP1A2-mediated phenacetin O-deethylation (IC50: 1.7 μM, Ki: 2.6 μM) and a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase. Additionally, it exhibits cytotoxicity to tumor cell lines U937 and HepG2.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TN3013

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H12N2O3

References

– OHMoTo T, et al. Studies on the constituents of Picrasma quassioides BENNET. III. The alkaloidal constituents. Chemical and pharmaceutical bulletin. 1984;32(9): 3579-3583.

CAS Number

– 18110-87-7

Molecular Weight

– C16H12N2O3

Compound Purity

– 0.9884

SMILES

– COc1c(OC)c(=O)n2c3ccccc3c3ccnc1c23

Pathway

– Microbiology/Virology|||Metabolism

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.