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NSC 370284

SKU T9949-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 102 CAD through 2,224 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– NSC 370284 is a small molecule that directly binds to and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T9949

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H25NO6

References

– Xi Jiang, et al. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia. Nature Communications volume 8, Article number: 2099 (2017).

CAS Number

– 116409-29-1

Molecular Weight

– C21H25NO6

Compound Purity

– 0.9616

SMILES

– COc1cc(cc(OC)c1OC)C(N1CCCC1)c1cc2OCOc2cc1O

Pathway

– Stem Cells|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.