BAY-8400
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BAY-8400

SKU T9498-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 123 CAD through 1,792 CAD

Products Details

Product Description

– BAY-8400 is a potent, selective, and orally active DNA-dependent protein kinase (DNA-PK) inhibitor (IC50 = 81 nM) that demonstrates synergistic efficacy when combined with targeted alpha therapies. BAY-8400 is applicable for cancer research [1].

Web ID

– T9498

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H17F2N5O

References

– Berger M, et al. BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies [published online ahead of print, 2021 Aug 24]. J Med Chem. 2021;10.1021/acs.jmedchem.1c00762.

Molecular Weight

– C21H17F2N5O

Compound Purity

– 0.9932

SMILES

– FC(F)C1=CN=CC(C2=CC=C(N=CC3=NN=C(C4=CCCOCC4)N35)C5=C2)=C1

Pathway

– PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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