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KU004
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– KU004, a potent dual EGFR/HER2 inhibitor, exhibits anticancer properties. It inhibits the proliferation of human breast cancer SKBR3 cells by inducing G1 phase arrest. KU004 blocks the activation of HER2, EGFR, and the downstream Akt and Erk pathways, primarily inducing apoptosis (Apoptosis) through the extrinsic pathway. Additionally, KU004 is a novel quinazoline derivative.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T89998
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H27ClFN4O2P
CAS Number
– 1260401-93-1
Molecular Weight
– C29H27ClFN4O2P
SMILES
– O=P1(C)CCN(CC#CC=2C=CC3=NC=NC(NC4=CC=C(OCC=5C=CC=C(F)C5)C(Cl)=C4)=C3C2)CC1
Pathway
– Cytoskeletal Signaling|||Angiogenesis|||JAK/STAT signaling|||PI3K/Akt/mTOR signaling|||MAPK|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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