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PROTAC CDK4/6 degrader 1
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– PROTAC CDK4/6 degrader 1 (Compound 7f) is a dual degrader of CDK4 and CDK6, with DC50 values of 10.5 nM and 2.5 nM, respectively. This compound effectively inhibits proliferation in Jurkat cells (IC50 of 0.18 μM), induces cell cycle arrest during the G1 phase, and triggers cell apoptosis (apoptosis).
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T88727
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C41H47N11O6
CAS Number
– 3025082-14-5
Molecular Weight
– C41H47N11O6
SMILES
– O=C1C=NC=2C=NC(=NC2N1C3CCCC3)NC4=CC=C(C=C4)N5CCN(CC5)CCCCC(=O)NCCNC6=CC=CC=7C(=O)N(C(=O)C67)C8C(=O)NC(=O)CC8
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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