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Locostatin

SKU T8823-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 62 CAD through 597 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Locostatin is a potent and cell permeable inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction and an inhibitor of cell migration.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8823

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H15NO3

Citations

– 1. Ye J J, Wei S L, Wei Y Y, et al.RKIP suppresses the influenza A virus‑induced airway inflammatory response via the ERK/MAPK pathway.International Journal of Molecular Medicine.2023, 51(1): 1-14.

References

– A M J , Stefania Greco A , B M S I A , et al. Locostatin, a disrupter of Raf kinase inhibitor protein, inhibits extracellular matrix production, proliferation, and migration in human uterine leiomyoma and myometrial cells[J]. Fertility and Sterility, 2016, 106( 6):1530-1538.

CAS Number

– 133812-16-5

Molecular Weight

– C14H15NO3

Compound Purity

– 0.9984

SMILES

– CC=CC(=O)N1C(Cc2ccccc2)COC1=O

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.