MSA-2

SKU T8798-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 2,048 CAD

Products Details

Product Description

– MSA-2 is an orally available non-nucleotide STING agonist. The non-covalent dimer of MSA-2 binds to STING with nanomolar affinity. It shows anti-tumor activity in syngeneic mouse tumor models, synergizes with anti-PD-1, stimulates tumor secretion of interferon-β, induces tumor regression, and has long-lasting anti-tumor immunity. [3]

Web ID

– T8798

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H14O5S

References

– Pan BS, et al. An orally available non-nucleotide STING agonist with antitumor activity. Science. 2020;369(6506):eaba6098.

CAS Number

– 129425-81-6

Molecular Weight

– C14H14O5S

Compound Purity

– 0.9888

SMILES

– COc1cc2cc(sc2cc1OC)C(=O)CCC(O)=O

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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