PROTAC BRAF-V600E degrader-1

SKU T8745-1 mg Category Brand:

Price range: 184 CAD through 2,672 CAD

Products Details

Product Description

– PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.

Web ID

– T8745

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C48H54F2N10O10S

References

– Han X R , Chen L , Wei Y , et al. Discovery of Selective Small Molecule Degraders of BRAF-V600E[J]. Journal of Medicinal Chemistry, 2020, XXXX(XXX).

CAS Number

– 2417296-84-3

Molecular Weight

– C48H54F2N10O10S

Compound Purity

– 0.9943

SMILES

– FC1=C(N2C=3C(C(=C2)C=4C=NC=NC4)=NC(N(C)C5CCN(C(CCOCCOCCOCCNC6=C7C(C(=O)N(C7=O)C8C(=O)NC(=O)CC8)=CC=C6)=O)CC5)=CC3)C(F)=CC=C1NS(CCC)(=O)=O

Pathway

– MAPK|||PROTAC

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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