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Guanfu base A
Price range: 130 CAD through 1,549 CAD
Products Details
Product Description
– Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
Web ID
– T8182
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H31NO6
References
– Sun J, et al. Guanfu base A, an antiarrhythmic alkaloid of Aconitum coreanum, Is a CYP2D6 inhibitor of human, monkey, and dog isoforms. Drug Metab Dispos. 2015 May;43(5):713-24.
CAS Number
– 1394-48-5
Molecular Weight
– C24H31NO6
Compound Purity
– 0.9985
SMILES
– [H][C@@]12CC34CC(=C)[C@]5([H])[C@@H](O)[C@@]3([H])[C@@]36C[C@H](C[C@@](C)(CN1C3[C@@]4(O)[C@@H]5OC(C)=O)[C@@]26[H])OC(C)=O
Pathway
– Metabolism|||Membrane transporter/Ion channel
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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