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Products Details
Product Description
– TWIK-1/TREK-1-IN-3 is a selective and potent inhibitor of the potassium channel TREK-1, effectively inhibiting TREK-1 homodimers and TWIK-1/TREK-1 heterodimers containing two-pore-domain potassium (K2p) channels. TWIK-1/TREK-1-IN-3 exhibits antidepressant activity and can be utilized in the study of depression.
Web ID
– T78870
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H27F3N2O2
References
– Lee EH, et al. Novel potent blockers for TWIK-1/TREK-1 heterodimers as potential antidepressants. Biomed Pharmacother. 2023 Sep;165:115139.
CAS Number
– 1440532-33-1
Molecular Weight
– C19H27F3N2O2
Compound Purity
– 0.9904
SMILES
– C([C@@H](COC1=CC=C(C(F)(F)F)C=C1)O)N2CCC(CC2)N3CCCC3
Pathway
– Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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