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YAP-TEAD-IN-3

SKU T77725-1 mg Category Small Compound Brand: TargetMol

Price range: 525 CAD through 3,168 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– YAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434). YAP-TEAD-IN-3 inhibits YAP reporter gene expression (IC50 = 0.048 μM) and NCI-H2052 cell proliferation (IC50 = 0.048 μM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T77725

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H26ClF2N3O4

References

– Saunders JT,et al. Targeting the YAP-TEAD interaction interface for therapeutic intervention in glioblastoma. J Neurooncol. 2021 Apr;152(2):217-231.

CAS Number

– 2714434-21-4

Molecular Weight

– C27H26ClF2N3O4

Compound Purity

– 0.9871

SMILES

– O=C(NC)C1=CN=C(OCCO)C(F)=C1C2=C3C[C@@]([C@H]4NCCC4)(OC3=CC(F)=C2Cl)C5=CC=CC=C5

Pathway

– Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.