YAP-TEAD-IN-3

SKU T77725-1 mg Category Brand:

Price range: 525 CAD through 3,168 CAD

Products Details

Product Description

– YAP-TEAD-IN-3 is an inhibitor of YAP/TAZ-TEAD interactions with an IC50 of 9 nM for Avi-human TEAD (4217-434). YAP-TEAD-IN-3 inhibits YAP reporter gene expression (IC50 = 0.048 μM) and NCI-H2052 cell proliferation (IC50 = 0.048 μM).

Web ID

– T77725

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H26ClF2N3O4

References

– Saunders JT,et al. Targeting the YAP-TEAD interaction interface for therapeutic intervention in glioblastoma. J Neurooncol. 2021 Apr;152(2):217-231.

CAS Number

– 2714434-21-4

Molecular Weight

– C27H26ClF2N3O4

Compound Purity

– 0.9871

SMILES

– O=C(NC)C1=CN=C(OCCO)C(F)=C1C2=C3C[C@@]([C@H]4NCCC4)(OC3=CC(F)=C2Cl)C5=CC=CC=C5

Pathway

– Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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