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NDI-091143

SKU T7424-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 48 CAD through 938 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– NDI-091143 is a potent, high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), indirectly disrupting citrate binding via an unexpected mechanism of inhibition.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7424

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H14ClF2NO5S

References

– Jia, Wei, Silvana, et al. An allosteric mechanism for potent inhibition of human ATP-citrate lyase[J]. Nature, 2019.

CAS Number

– 2375840-87-0

Molecular Weight

– C20H14ClF2NO5S

Compound Purity

– 0.9861

SMILES

– COC(=O)c1cc(Cl)c(O)c(c1)S(=O)(=O)Nc1cc(c(F)cc1F)-c1ccccc1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.