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Nardosinone
Price range: 48 CAD through 501 CAD
Products Details
Product Description
– 1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. 3. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. 4. The enhancement of NGF-induced neurite outgrowth from PC12D cells by Nardosinone involves activation of a down-stream step of the MAP kinase-dependent cascade of NGF coupled with PKC.
Web ID
– T6S1740
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H22O3
References
– Du M , Huang K , Gao L , et al. Nardosinone Protects H9c2 Cardiac Cells from Angiotensin II-induced Hypertrophy[J]. Journal of Huazhong University of Science and Technology, 2013, 33(6):822-826.
CAS Number
– 23720-80-1
Molecular Weight
– C15H22O3
Compound Purity
– 0.9882
SMILES
– C[C@@H]1CCC=C2C(=O)C[C@H]3OOC(C)(C)[C@H]3[C@@]12C
Pathway
– Others
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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