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Spliceostatin A
1,992 CAD
Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Spliceostatin A is an anticancer agent and splicing inhibitor that inhibits the splicing mechanism of the spliceosome and inhibits mitotic clonal expansion and adipogenesis.Spliceostatin A induces cell cycle arrest in the G1 and G2/M phases, and induces apoptosis.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T69308
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H43NO8
References
– Larrayoz M, et al. The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-Leukemia. 2016 Feb;30(2):351-60.
CAS Number
– 391611-36-2
Molecular Weight
– C28H43NO8
Compound Purity
– 0.9466
SMILES
– O[C@H]1[C@@]2(C[C@](OC)(C)O[C@@H]1/C=C/C(=C/C[C@H]3[C@@H](C)C[C@@H](NC(/C=C[C@@H](OC(C)=O)C)=O)[C@@H](C)O3)/C)CO2
Pathway
– Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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