T0901317

SKU T6690-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 51 CAD through 331 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6690

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H12F9NO3S

Citations

– 1. Li C, Wu H, Na H S T, et al. Neuronal-Microglial Liver X receptor β Activating Decrease Neuroinflammation and Chronic Stress-induced Depression-Related Behavior in Mice. Brain Research. 2022: 148112. 2. Liu Y, Wang Z, Jin H, et al.Squalene-epoxidase-catalyzed 24 (S), 25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity.Cell Reports.2024, 43(4).

References

– Repa JJ, et al. Science, 2000, 289(5484), 1524-1529.

CAS Number

– 293754-55-9

Molecular Weight

– C17H12F9NO3S

Compound Purity

– 0.9943

SMILES

– C(C(F)(F)F)(C(F)(F)F)(O)C1=CC=C(N(S(=O)(=O)C2=CC=CC=C2)CC(F)(F)F)C=C1

Pathway

– Metabolism|||Apoptosis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.