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Bexarotene
Price range: 48 CAD through 418 CAD
Products Details
Product Description
– Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
Web ID
– T6410
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H28O2
Citations
– 1. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks. Chemical Science. 2020, 11(7): 1775-1797.
2. Qiu Y, Sun Y, Xu D, et al. Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue. EBioMedicine. 2018, 37: 344-355.
3. Ren Q, Xie X, Zhao C, et al. 2, 2′, 4, 4′-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation. Chemical Research in Toxicology. 2022
4. Dou X, Huo T, Liu Y, et al.Discovery of novel and selective farnesoid X receptor antagonists through structure-based virtual screening, preliminary structure-activity relationship study, and biological evaluation.European Journal of Medicinal Chemistry.2024: 116323.
References
– Zhang C, et al. Clin Cancer Res, 2002, 8(5), 1234-1240.
CAS Number
– 153559-49-0
Molecular Weight
– C24H28O2
Compound Purity
– 0.9915
SMILES
– CC1(C)C=2C(C(C)(C)CC1)=CC(C)=C(C(=C)C3=CC=C(C(O)=O)C=C3)C2
Pathway
– Metabolism|||Autophagy
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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