(R)-(-)-Gossypol acetic acid

SKU T6396-1 g Category Brand:

Price range: 53 CAD through 2,288 CAD

Products Details

Product Description

– (R)-(-)-Gossypol acetic acid (AT101 acetate), the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL, and Mcl-1 with Ki values of 0.32 μM, 0.48 μM, and 0.18 μM, respectively; it does not inhibit the BIR3 domain or BID. [Phase 2]

Web ID

– T6396

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H30O8·C2H4O2

References

– Wang G, et al. J Med Chem. 2006, 49(21), 6139-6142.

CAS Number

– 866541-93-7

Molecular Weight

– C30H30O8·C2H4O2

Compound Purity

– 0.9673

SMILES

– CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O

Pathway

– Apoptosis|||Autophagy

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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