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AR42

SKU T6392-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 54 CAD through 1,466 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6392

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H20N2O3

Citations

– 1. Zhu Y, Yuan T, Zhang Y, et al. AR-42: A Pan-HDAC Inhibitor with Antitumor and Antiangiogenic Activities in Esophageal Squamous Cell Carcinoma. Drug Design, Development and Therapy. 2019, 13: 4321 2. Zhu Y, Yuan T, Zhang Y, et al. AR-42: A Pan-HDAC Inhibitor with Antitumor and Antiangiogenic Activities in Esophageal Squamous Cell Carcinoma. Drug Design, Development and Therapy. 2019, 13: 4321 3. Su L, Wang S, Yuan T, et al. Anti-oral Squamous Cell Carcinoma Effects of a Potent TAZ Inhibitor AR-42. Journal of Cancer. 2020, 11(2): 364-373.

References

– Lu Q, et al. J Med Chem, 2005, 48(17), 5530-5535.

CAS Number

– 935881-37-1

Molecular Weight

– C18H20N2O3

Compound Purity

– 0.9846

SMILES

– CC(C)[C@H](C(=O)Nc1ccc(cc1)C(=O)NO)c1ccccc1

Pathway

– Chromatin/Epigenetic|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.