Download Files:
A 922500
Price range: 69 CAD through 1,413 CAD
Products Details
Product Description
– A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor of human and mouse DGAT-1 with IC50 values of 7 nM and 24 nM, respectively, demonstrating good selectivity over related acyltransferases, hERG, and a panel of anti-targets.
Web ID
– T6365
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H24N2O4
Citations
– 1. Masouleh S K. Lipid droplet formation drives pathogenic ILC2 responses in airway inflammation. Immunity. 2020
2. Karagiannis F, Masouleh S K, Wunderling K, et al. Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation. Immunity. 2020, 52(4): 620-634. e6.
3. Wang W, Qu Y, Wang X, et al.Genetic variety of ORF3a shapes SARS‐CoV‐2 fitness through modulation of lipid droplet.Journal of Medical Virology.2023
References
– King AJ et al. J Pharmacol Exp Ther. 2009, 330(2), 526-531.
CAS Number
– 959122-11-3
Molecular Weight
– C26H24N2O4
Compound Purity
– 0.9766
SMILES
– OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2)cc1
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
