NRX-103094
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NRX-103094

SKU T63427-1 mg Category Brand:

Price range: 107 CAD through 2,192 CAD

Products Details

Product Description

– NRX-103094 is a potent enhancer of the interaction between β-catenin and the homologous E3 ligase SCFβ-TrCP, increasing the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM.

Web ID

– T63427

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H11Cl2F3N2O4S

References

– Kyle R Simonetta, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10(1):1402.

CAS Number

– 2763260-36-0

Molecular Weight

– C20H11Cl2F3N2O4S

Compound Purity

– 0.995

SMILES

– S(C1=C(C(NC2=CC(C(O)=O)=CC=C2)=O)C(=O)NC(C(F)(F)F)=C1)C3=C(Cl)C=CC=C3Cl

Pathway

– Stem Cells|||Cytoskeletal Signaling

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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