Download Files:
GSK461364
Price range: 50 CAD through 2,048 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1.The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T6282
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H28F3N5O2S
Citations
– 1. Yu Z, Deng P, Chen Y, et al. Inhibition of the PLK1‐Coupled Cell Cycle Machinery Overcomes Resistance to Oxaliplatin in Colorectal Cancer. Advanced Science. 2021: 2100759.
2. Yu Z, Deng P, Chen Y, et al. Inhibition of the PLK1‐Coupled Cell Cycle Machinery Overcomes Resistance to Oxaliplatin in Colorectal Cancer. Advanced Science. 2021: 2100759.
References
– Gilmartin AG, et al. Cancer Res, 2009, 69(17), 6969-6977.
CAS Number
– 929095-18-1
Molecular Weight
– C27H28F3N5O2S
Compound Purity
– 0.99
SMILES
– C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(CN3CCN(C)CC3)cc12)c1ccccc1C(F)(F)F
Pathway
– Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
Proudly representing
150+ years of combined research-supply heritage
