Download Files:
DC-LC3in-D5
Price range: 168 CAD through 4,144 CAD
Products Details
Product Description
– DC-LC3in-D5 is a potent and selective covalent inhibitor of LC3A/B that disrupts autophagy by covalently binding to Lys49 on LC3B (IC₅₀ = 200 nM), resulting in impaired LC3B lipidation, accumulation of the autophagy substrate p62, and a significant reduction in the formation of autophagosome vesicles.
Web ID
– T61871
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H22Cl2N2O3
CAS Number
– 2868312-73-4
Molecular Weight
– C19H22Cl2N2O3
Compound Purity
– 0.9979
SMILES
– O=C1C(=CNCCN2CCOCC2)C(=O)CC(C=3C=CC=C(Cl)C3Cl)C1
Pathway
– Autophagy
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
